Dexamyl or Drinamyl in the UK was a brand name combination drug composed of sodium amobarbital previously called amylbarbitone and its brand name was Amytal and dextroamphetamine sulfate Dexedrine within the same pill. It was widely abused, and is no longer manufactured. Racemic amphetamine sulfate had already been marketed over-the-counter OTC since as an nasal decongestant inhaler device under the brand name Benzedrine, and also as an oral tablet since Dexamyl utilized its enantiopure isomer of greater central nervous system CNS selectivity, dextroamphetamine sulfate, to elevate mood and suppress appetite, whereas the concomitant barbiturate was included to broadly counteract potential adverse effects from dextroamphetamine. Its name is a portmanteau of dextro – amphetamine and amyl – barbitone. Dexamyl was discontinued in by SKF in favor of monoamine oxidase inhibitors MAOIs and tricyclic antidepressants TCAs which were recently developed and shared treatment indications with Dexamyl yet lacked the high dependence potential and abuse liability which characterized long-term Dexamyl usage. British prime minister Anthony Eden was prescribed Dexamyl; he was using it to treat abdominal pain.
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