These complex relationships may be particularly relevant in subgroups of individuals e. The review found collated relevant studies, covering a wide variety of potential risk factors, finding the most evidence around diabetes, high blood pressure and mental health. Accelerated progression from mild cognitive impairment to dementia in people with diabetes. J Clin Epidemiol. Comparability of cohorts on the basis of the design or analysis. Metabolic syndrome One identified study grade 2 evidence found that metabolic syndrome predicted any-cause dementia in a specific type of MCI, termed “amnestic MCI”. Multiple studies from a single cohort We did identify multiple papers on MeDi from the same cohort e. Cognitive dysfunction is associated with poor diabetes control in older adults. What kind of research was this? In the other study, the rate of incident dementia per person-years was four times higher in people with MetS who had hypertension when compared to people without: However, ways to prevent the onset of dementia are unclear.
Diabetes may increase your risk of Alzheimer’s. But blood sugar control, exercise and a healthy diet may help. There’s a lot of research suggesting a connection between diabetes and Alzheimer’s — though those connections aren’t yet fully understood. Not all studies confirm the connection, but many do suggest that people with diabetes, especially type 2 diabetes, are at higher risk of eventually developing Alzheimer’s dementia or other dementias. Research is still unclear on whether taking steps to prevent or control diabetes may help reduce your risk of cognitive decline. Diabetes can cause several complications, such as damage to your blood vessels. Diabetes is considered a risk factor for vascular dementia. This type of dementia occurs due to brain damage that is often caused by reduced or blocked blood flow to your brain. Many people with diabetes have brain changes that are hallmarks of both Alzheimer’s disease and vascular dementia. Some researchers think that each condition fuels the damage caused by the other. Ongoing research is aimed at trying to better understand the link between Alzheimer’s and diabetes. That link may occur as a result of the complex ways that type 2 diabetes affects the ability of the brain and other body tissues to use sugar glucose and respond to insulin.
Hypoglycemic episodes and risk of dementia in older patients with Type 2 diabetes mellitus. Soc Psychiatry Psychiatr Epidemiol 53, — Insulin receptors and insulin die in the brain: review and clinical implications. Helpful relative risks of developing any cause dementia and VaD in people mci? T2D have been estimated to be 1. In addition, strict diabetic control has diabetic demonstrated to carry risk for certain diabetic populations. Home About Contact. Review Manager RevMan. Insulin resistance is associated diet the pathology of Alzheimer disease: the Hisayama study. Importantly, the beneficial effect on cognition of some antidiabetic treatment strategies may go further than for glucose-lowering effect, and may therefore extend to populations beyond diabetic subjects.